O'Keeffe's Working Hands Creme works because IT'S DIFFERENT. The unprecedented effectiveness of O'Keeffe's Working Hands and Healthy Feet Creme is due to its chemical humectant, an occlusive agent, and a radically different pH in an unconventional formulation that has proven to increase hydration and circulation. O'Keeffe's creates the perfect microenvironment to both initiate and stimulate skin cell growth and repair.